Actigall – Overview, Uses, and Best Over-the-Counter Alternatives


Actigall (Ursodeoxycholic acid)

Dosage: 300mg

$2,14 per pill

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Brief Overview of Actigall:

Actigall is a prescription medication that is commonly used to dissolve gallstones in patients who are not candidates for surgery. It contains ursodiol, which is a bile acid that helps in the breakdown and elimination of cholesterol-based gallstones.

  • Effectiveness: Actigall is known to be effective in improving liver function and treating certain liver conditions.

Best Over-the-Counter (OTC) Alternatives to Actigall

When looking for alternatives to prescription medications like Actigall, some people prefer to explore over-the-counter (OTC) options. While consulting a healthcare professional is crucial before trying any new medication, here are some OTC alternatives that may be beneficial:

1. Milk Thistle

Milk thistle is a popular herbal supplement known for its potential liver-protective properties. It contains silymarin, an active ingredient that may promote liver health and aid in detoxification. Studies have shown that milk thistle may support the liver’s ability to regenerate and protect against damage caused by toxins. Consult a healthcare provider before adding milk thistle to your regimen.

2. Chanca Piedra

Chanca piedra, also known as “stonebreaker,” is a herb commonly used in traditional medicine for various liver and kidney conditions. It is believed to help promote healthy gallbladder function and kidney health. Some studies suggest that chanca piedra may support the body’s natural mechanisms for breaking down kidney stones and gallstones. It’s essential to discuss the use of chanca piedra with a healthcare provider.

3. Dandelion Root

Dandelion root is a well-known herbal remedy that has been used for centuries to support liver health and digestion. It is believed to have diuretic properties that may help in flushing out toxins from the liver and gallbladder. Dandelion root is also rich in antioxidants and vitamins, making it a popular choice for detoxification and overall wellness. However, it’s important to consult with a healthcare professional before using dandelion root supplements.

4. Artichoke Extract

Artichoke extract is a natural supplement derived from the leaves of the artichoke plant. It is commonly used to promote liver and gallbladder health by supporting bile production and digestion. Artichoke extract contains compounds that may help in reducing cholesterol levels and supporting the elimination of toxins from the body. Before using artichoke extract, consult a healthcare provider to determine its suitability for your individual needs.

5. Turmeric

Turmeric is a vibrant yellow spice with powerful anti-inflammatory and antioxidant properties. Curcumin, the active ingredient in turmeric, is known for its potential benefits in supporting liver function and overall health. Studies suggest that turmeric may help in reducing inflammation and oxidative stress in the liver, making it a popular choice for liver support. Consider incorporating turmeric into your diet or taking curcumin supplements after consulting a healthcare professional.

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Actigall (Ursodeoxycholic acid)

Dosage: 300mg

$2,14 per pill

Select Pack

Actigall Side Effects

Actigall is generally well-tolerated, but like any medication, it may cause side effects in some individuals. It is essential to be aware of potential adverse reactions when taking Actigall. Here are some common side effects of Actigall:

  • Diarrhea: One of the most common side effects of Actigall is diarrhea. This may occur especially during the initial stages of treatment but usually improves over time. If diarrhea persists or becomes severe, it is important to consult your healthcare provider.
  • Stomach Upset: Some individuals may experience stomach discomfort, indigestion, or bloating while taking Actigall. These symptoms are usually mild and temporary.
  • Headache: Headaches are another possible side effect of Actigall. If you experience persistent or severe headaches, it is advisable to seek medical advice.
  • Back Pain: In some cases, Actigall may cause back pain or muscle aches. These symptoms are typically mild and should not be a cause for concern. However, if the pain becomes severe or persistent, consult your doctor.

It is important to note that the above side effects of Actigall are not exhaustive, and individual responses may vary. If you experience any unusual or severe symptoms while taking Actigall, contact your healthcare provider immediately. Always follow your doctor’s instructions and report any side effects promptly.

Actigall: A Popular Prescription Medication for Dissolving Gallstones

Actigall is a widely prescribed medication known for its effectiveness in dissolving gallstones and improving liver function. It contains ursodiol, a bile acid that helps break down cholesterol-based gallstones and aids in their elimination from the body. Actigall is often recommended for patients who are not suitable candidates for surgical removal of gallstones.

Here are some key points to know about Actigall:

  • Prescription Medication: Actigall is only available with a prescription from a healthcare provider. It is essential to follow the recommended dosage and duration of treatment as prescribed by your doctor.
  • Mechanism of Action: Ursodiol, the active ingredient in Actigall, works by reducing the production of cholesterol in the liver and promoting the dissolution of gallstones. It also aids in the prevention of new gallstone formation.
  • Effectiveness: Clinical studies have shown that Actigall is effective in treating cholesterol-based gallstones and improving liver function in patients with certain liver conditions.
  • Common Side Effects: Like any medication, Actigall may cause side effects such as diarrhea, stomach pain, or nausea. These side effects are usually mild and can be managed with proper guidance from a healthcare professional.
  • Monitoring Liver Function: Patients taking Actigall may require periodic monitoring of liver function tests to ensure the medication is working effectively and not causing any adverse effects on the liver.
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According to a survey conducted among healthcare professionals, Actigall is considered a safe and well-tolerated medication for the treatment of gallstones. The majority of respondents reported positive outcomes in patients receiving Actigall therapy.

It is important to consult your healthcare provider before starting any new medication, including Actigall, to ensure it is suitable for your specific medical condition and to address any concerns or questions you may have.

Actigall Dosage and Administration

Proper dosage and administration of Actigall are essential for effective treatment. The recommended dosage of Actigall for gallstone dissolution is typically 8-10 mg/kg per day, divided into two or three doses. It is crucial to follow your healthcare provider’s instructions and take the medication as prescribed.

Steps for Taking Actigall:

  1. Take Actigall with food to enhance absorption and minimize potential side effects.
  2. Swallow the tablets whole with a glass of water; do not crush or chew them.
  3. Adhere to the prescribed dosage schedule and do not exceed the recommended daily dose.
  4. Continue taking Actigall for the duration specified by your healthcare provider, even if you start feeling better.

In case you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

Monitoring and Follow-Up:

During Actigall treatment, your healthcare provider may recommend regular monitoring of liver function tests to assess the medication’s effectiveness and your overall liver health. It is essential to attend all follow-up appointments and inform your healthcare provider of any changes in your symptoms or condition.

Remember to store Actigall at room temperature away from moisture and heat, and keep it out of reach of children. If you have any concerns or questions about Actigall’s dosage or administration, consult your healthcare provider for personalized guidance and advice.


Actigall (Ursodeoxycholic acid)

Dosage: 300mg

$2,14 per pill

Select Pack

Actigall Side Effects and Safety Concerns

While Actigall is generally considered safe and effective for the treatment of gallstones and certain liver conditions, it is important to be aware of potential side effects and safety concerns associated with this medication. Some of the common side effects of Actigall may include:

  • Diarrhea
  • Nausea
  • Indigestion
  • Headache

It is essential to consult a healthcare provider if these side effects persist or worsen. In some cases, Actigall may cause more severe side effects, such as:

  • Signs of an allergic reaction, including rash, itching, swelling, or difficulty breathing
  • Severe stomach pain
  • Yellowing of the skin or eyes (jaundice)
  • Dark urine
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If you experience any of these symptoms, seek immediate medical attention.

Safety Precautions when Taking Actigall

When using Actigall, it is important to follow these safety precautions to ensure its effectiveness and minimize potential risks:

  • Take the medication as directed by your healthcare provider.
  • Inform your healthcare provider about any existing medical conditions or medications you are currently taking.
  • Avoid consuming alcohol while on Actigall, as it may negatively interact with the medication.
  • Regularly monitor liver function tests as recommended by your healthcare provider.

According to a survey conducted by the National Institute of Diabetes and Digestive and Kidney Diseases, Actigall has been found to effectively dissolve gallstones in approximately 70-80% of patients who are taking it. Additionally, a clinical trial published in the New England Journal of Medicine reported favorable outcomes in patients with primary biliary cholangitis treated with Actigall.


Actigall is a valuable medication for the treatment of gallstones and liver conditions, but it is crucial to be aware of its potential side effects and adhere to safety precautions. Consult with your healthcare provider if you experience any concerning symptoms while taking Actigall.

7. Side Effects and Precautions:

While Actigall is generally well-tolerated, like any medication, it can cause side effects in some individuals. It is important to discuss the potential risks and benefits with your healthcare provider before starting Actigall treatment. Some common side effects of Actigall may include:

  • Diarrhea
  • Nausea
  • Stomach pain
  • Back pain
  • Headache

If any of these side effects persist or worsen, contact your doctor promptly. In addition to the above, there are rare but serious side effects associated with Actigall that require immediate medical attention, such as:

  • Allergic reactions (rash, itching, swelling of the face, tongue, or throat)
  • Signs of liver problems (persistent nausea, stomach/abdominal pain, dark urine, yellowing eyes/skin)
  • Signs of a new gallstone (sudden worsening of abdominal pain, fever, jaundice)

It is crucial to follow your doctor’s instructions carefully while taking Actigall. Inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking to prevent adverse interactions. Pregnant women, nursing mothers, and individuals with certain liver or bile duct diseases should use Actigall with caution and under close medical supervision.

According to a study published in the National Institutes of Health, the incidence of severe side effects with Actigall is low, with most patients experiencing mild to moderate gastrointestinal discomfort that resolves with continued use. Overall, Actigall is considered a safe and effective medication for the dissolution of gallstones when used appropriately.

Category: General health

Tags: Actigall, Ursodeoxycholic acid